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ea0067o53 | Oral Presentations | EYES2019

Seasonal changes of serum gonadotropins and testosterone in men: a reappraisal from a large data set of real-world observations over eight years

Spaggiari Giorgia , Granata Antonio RM , Setti Monica , Tagliavini Simonetta , Trenti Tommaso , Simoni Manuela , Santi Daniele

Objective: Environmental rhythmicity seems able to affect the hypothalamic-pituitary-gonadal axis in animals, but the extent of its influence in humans is still controversial. This study was designed to evaluate seasonal fluctuations of the main hormones involved in the hypothalamic-pituitary-gonadal axis in men, using a big data approach.Methods: An observational, retrospective, big data trial was carried out, including all testosterone, luteinizing hor...

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ea0014p576 | (1) | ECE2007

Impaired GH secretion in women with HIV-related lipodystrophy

Rochira Vincenzo , Zirilli Lucia , Madeo Bruno , Caffagni Giovanni , Sanguanini Alessia , Granata Antonio RM , De Santis Maria Cristina , Orlando Gabriella , Squillace Nicola , Guaraldi Giovanni , Carani Cesare

Introduction: Patients with human immunodeficiency virus-1 (HIV-1) infection develop a lipodystrophic syndrome characterised by accumulation of central fat both in visceral and in subcutaneous compartment. In recent studies approximately 20% of male patients with HIV-related lipodystrophy presented an inadequate peak of GH secretion in response to GHRH-arginine testing, which is strongly inversely related to visceral adipose tissue-(VAT).Aim of the study...

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Endocrine Abstracts

Seasonal changes of serum gonadotropins and testosterone in men: a reappraisal from a large data set of real-world observations over eight years

Impaired GH secretion in women with HIV-related lipodystrophy

BiosciAbstracts